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In the E2 reaction, the oxygen from the hydroxide attacks the "beta" hydrogen, deprotinating it and allowing the electron to travel and form a double bond. Bromide is a leaving group. We get 2-butene as well as water and the bromide ion. But we have two products from this reaction: trans-2-butene and cis-2-butene. We also have (2,S)-butanol. 38. The enthalpy change for the reaction between aqueous sodium hydroxide solution and aqueous hydrochloric acid was determined by the following method: • Aqueous hydrochloric acid was titrated against 25.0 cm3 of 1.50 mol dm–3 aqueous sodium hydroxide solution using a suitable indicator. The mean (or average) titre was 22.75 cm3. What is the major organic product obtained from the reaction of 2,2-dimethyl-1-propanol aqueous HBr at reflux? a. 1-bromo-2,2-dimethylpropane b. 1-bromo-2-methylbutane